What is Verquvo (vericiguat) for?
Buy Verquvo (vericiguat). Verquvo (vericiguat) is a medicine for adults with long-term heart failure. It helps those who have been in the hospital recently or needed IV medicines. It works best for people with an ejection fraction of less than 45%.
- to reduce the risk of dying and
- to reduce the need to be hospitalized
It comes in tablet form, with 2.5 mg, 5 mg, or 10 mg of vericiguat in each.
How does Verquvo (vericiguat) work?
Vericiguat works by boosting soluble guanylate cyclase (sGC). This enzyme helps blood vessels relax. It does this by making more cGMP, which is important for the heart and blood vessels.
Heart failure happens when there’s not enough nitric oxide (NO). This makes the heart weak and unable to pump enough blood.
Vericiguat helps by making sGC work better. This lowers cGMP levels, making blood vessels relax and widen.
Where has Verquvo (vericiguat) been approved?
Verquvo (vericiguat) has been approved in several places:
- The Food and Drug Administration (FDA), USA on January 19, 2021.
- The Pharmaceuticals and Medical Devices Agency (PMDA), Japan on June 23, 2021
- The European Medicines Agency (EMA) on July 21, 2021.
This medicine might also be approved in other areas. If you have questions, contact our support team.
How is Verquvo (vericiguat) taken?
The usual dose is:
- 2.5 mg tablets taken orally 1 time each day with food
- Every 2 weeks, the dose should be doubled to reach 10 mg once daily, to find the best dose for you.
If you miss a dose, take it as soon as you remember. Do not take two doses in one day.
Warning: do not take Verquvo (vericiguat) if you are taking another sGC stimulator. Ask your healthcare provider if you are not sure if you are taking an sGC medicine.
For more details on dosage and administration, see the official prescribing information in our references section.
Note: Please consult with your treating doctor for personalised dosing.
Are there any known adverse reactions or side effects of Verquvo (vericiguat)?
Common adverse reactions
The most common side effects ( ≥5% of patients) include:
- Low blood pressure (hypotension)
- Low red blood cells (anemia)
Serious adverse reactions
The serious side effects listed include:
- Severe breathing problems (respiratory failure)
- Internal bleedings (hemorrhage)
- Blood clots (thrombosis)
Use in a specific population
Verquvo (vericiguat) is dangerous for a fetus. It’s best to avoid breastfeeding or getting pregnant. Women who might get pregnant should use birth control while taking it and for 3 weeks after stopping.
For a full list of side effects and reactions, see the official prescribing information.