What is Vyndaqel (tafamidis)?
Buy Vyndaqel (tafamidis). Vyndaqel (tafamidis) is a medicine for treating a rare disease called transthyretin amyloidosis. It helps slow down nerve damage in patients with early symptoms. It’s the first drug to stop a protein called transthyretin from misfolding into harmful amyloids.
It comes in capsules, each with 20mg of tafamidis.
Who is Vyndaqel (tafamidis) for?
Vyndaqel (tafamidis) is for adults with a specific type of nerve disease called TTR-FAP.
This disease damages nerves, leading to weakness, numbness, and pain in hands and feet.
How does Vyndaqel (tafamidis) work?
Transthyretin amyloidosis is caused by a faulty protein called transthyretin (TTR). This protein breaks easily, forming harmful amyloid fibrils in the body. These fibrils damage tissues and organs, stopping them from working right.
The active part of Vyndaqel, tafamidis, stabilises the faulty protein. It keeps the protein from breaking, stopping amyloid fibrils from forming. This slows down the disease’s progress.
Where has Vyndaqel (tafamidis) been approved?
Vyndaqel (tafamidis) has been approved in many places for treating TTR-FAP. These include:
- EMA (EU), November 2011
- FDA (USA), May 2019
- Health Canada, January 2020
- PMDA (Japan), September 2013
- TGA (Australia), March 2020
It’s also approved in Brazil, Argentina, and Russia. Countries like Australia have given it orphan drug status. Orphan drug status helps speed up the development of medicines for rare diseases.
Remember, this medicine might be approved in other places too. If you have questions, our support team can help.
Always talk to a doctor before taking any medicine. The FDA has warned drugmakers in India about medicine quality.
How is Vyndaqel (tafamidis) taken?
The usual dose is:
- 20 mg orally once daily.
For more details on dosage and how to take it, see the official prescribing information. It’s in our references section.
Remember, your doctor will give you the right dose for you.
Are there any known side effects or adverse reactions of Vyndaqel (tafamidis)?
Possible Side Effects
The most common side effects listed in the prescribing information include:
- diarrhoea
- urinary tract infection (symptoms may include: pain or a burning sensation when you urinate or a frequent need to urinate)
- vaginal infection in women
- stomach ache or abdominal pain.
Use in specific populations
It is advised to avoid pregnancy and breastfeeding during and for one month after treatment with Vyndaqel (tafamidis).
For a comprehensive list of side effects and adverse reactions please refer to the official prescribing information.